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Year : 2015  |  Volume : 2  |  Issue : 3  |  Page : 155-160

Metabolic syndrome in menopausal women: Modulation of contributory inflammatory markers by dietary substrates

1 Vasudha Clinic, Santacruz (W); Unit of Endocrine and Metabolic Disorders, Medical Research Centre, Kasturba Health Society, Medical Research Center of Kasturba Health Society, Mumbai, India
2 Department of Food Science and Nutrition, SNDT Women's University, Mumbai, Maharashtra, India

Correspondence Address:
Rama Vaidya
Medical Research Centre, Kasturba Health Society, Vile Parle (West), Mumbai
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2347-9906.162342

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Menopausal transition (MT), a state of hormonal turbulence, is fraught with a possibility of weight gain, visceral obesity, and development of metabolic syndrome (MS). Though the weight gain in postmenopausal women seems to be an age-related phenomenon, a change in body composition with the resultant android type of obesity (visceral obesity) from premenopausal gynecoid phenotype is attributed to MT. Several studies including from India have conclusively shown that there is significantly higher prevalence of MS among postmenopausal women as compared to premenopausal women. MS is a forerunner of type 2 diabetes mellitus (DM) and cardiovascular diseases (CVD). Obesity particularly central adiposity, MS, DM, and CVD are all considered as low-grade chronic inflammatory diseases. Can administration of anti-inflammatory dietary substances attenuate menopausal MS? The issue of protection from inflammation can be examined from two perspectives: Using a reductionist approach by examining the effects of individual nutrients and by using a more holistic perspective by examining foods and diets in toto. Here we review both the approaches vis-ΰ-vis their anti-inflammatory actions.

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