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REVIEW ARTICLE
Year : 2015  |  Volume : 2  |  Issue : 1  |  Page : 30-34

Cancer and obesity: The cause, the connect, and the way ahead


Department of Minimal Invasive and Bariatric Surgery, Chairman and Chief Surgeon Surgical Registrar Surgical Registrar, Consultant Gynaecologist Consultant Surgeon, LifeLine RIGID Hospitals, Chennai, India

Correspondence Address:
S Akbar
Life Line Rigid Hospital Pvt., Ltd., 47/3, New Avadi Road, Kilpauk, Chennai - 600 010
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2347-9906.148609

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This is been a remarkable amount of research linking obesity and cancer in the past few years. There seems to be a definitely increased incidence of certain cancers such as breast, esophagus, colorectal and endometrial, in patients with high body mass index. This article looks at the associations between obesity and these cancers, outlines the postulated mechanisms that account for the increased incidences, and highlights some putative strategies to utilize these mechanisms to battle neoplasia. The final part of the article connects the decreased incidence of malignancy after bariatric surgery with the postulated anticancerous mechanisms of metabolic surgery. The available data over the last few years has been accumulated, and the most important scientific points have been culled out for practicing surgeons and researchers.


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